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Belarusian scientists model HIV treatment compounds

The principal researcher of the Belarusian Institute of Bioorganic Chemistry Alexander Andrianov announced that with the help of a computer, Belarusian scientists modeled chemical compounds which will be promising in the development of the HIV drug. The project manager mentioned that the compounds passed a computer pretest. The United Institute of Informatics Problems of Belarus used supercomputers during the test. Today more than 20 different medicines are used to cure HIV. However, the virus mutates and the drugs become less effective. Scientists work on new treatments.

The executive director of the United Institute of Informatics Problems Alexander Tuzikov described the process of the research.

“With the help of computers, we modeled chemical compounds based on one of the reaction inhibitors for HIV. We searched through chemical compounds databases some combinations which can be used as reaction inhibitors for HIV. To select the necessary compounds, we applied extensive modeling exercises.”

Though most compounds can be bought, some of them have to be synthesized.

With computer modeling and compounds testing, scientists got the basic data to continue the work on new HIV drugs. This research of the Belarusian scientists is among the top 100 basic and applied researches of the Belarusian National Academy of Science. 

In 2014, UNAIDS experts suggested that HIV could be stopped by the year 2030. So, by 2020 more than $30 billion need to be invested in drugs development.

Russian scientists are in search of new methods of HIV treatment as well. The Peter the Great St. Petersburg Polytechnic University won a grant from the Russian Science Foundation. Scientists found out the particle called bottleneck that cause the HIV infection. Due to its discovery, Russian scientists now focus on contagion process. The research manager Andrey Kozlov, Doctor of Biological Sciences, hopes that by 2030 they will find effective treatment for HIV.

On January 1, 2017, 22,218 people in Belarus were HIV infected. In 2016, there were 2,391 cases of infection; in 2015 there were 2,305 cases. It means that among every 100 Belarusian citizens there are 25.2 infected people (24.3 was in 2015). In most cases, the infection is transmitted sexually (60.2%).

Belarusian scientists model HIV treatment compounds